guia de dosagem · tal como está impresso em cada tampa
Tirzepatide 40
once weekly · 133 µg por clique · 300 cliques por caneta
Tirzepatide 40
once weekly · 133 µg por clique · 300 cliques por caneta
fase 01 Marcador de posição, caneta na dose inicial 
weeks 1–4 the on-ramp
2.5 mg · 19 cliques
once weekly · the studied starting dose
Tirzepatide's titration is the best-mapped in the incretin class. The opening dose is deliberately sub-therapeutic, it exists to build tolerance, not to move the curve. Little change in month one is the design, not a shortfall.
✦same weekday, morning or evening, pick one and keep it
✦mild GI markers in week one are common in the literature
✦fresh needle each time, pen refrigerated between doses
weeks 4–8 the working range
5 mg · 38 cliques
once weekly · where the phase-3 results begin
From week five the reference schedule enters the band where clinical results were recorded. Many research protocols hold here for months, the card only steps up again if the trend stalls for three-plus weeks.
✦hold the lowest dose that keeps the trend moving
✦protein reference ~1.6 g/kg to protect lean mass
✦rotate the injection site each week
fase 02 Marcador de posição, seletor na dose aumentada
fase 03 Marcador de posição, dose de referência completa 
weeks 8+ the ceiling, if needed
7.5 mg · 56 cliques
once weekly · only after 8+ settled weeks
The upper step of this pen. The published programme ran doses higher still, but most of the effect in the data arrives well below the maximum. Durability beats intensity across a twelve-month horizon.
✦escalate only if progress genuinely plateaus
✦a missed week: within four days or skip, never double
✦reorder early so cold shipping never interrupts the schedule
✦ Este guia reproduz o cartão de dosagem impresso e a titulação de investigação publicada, é uma referência para investigação de laboratório, não um conselho médico. Consulte o aviso de utilização em investigação antes de o utilizar.
